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eMolecules EMOLECULES INC
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Anti-Nectin-4 Antibody (Enfortumab) (CAS No 1448664-46-7) is a therapeutic monoclonal antibody used in biomedical research focused on targeted cancer therapy It originates from studies advancing the treatment of tumors expressing Nectin-4 a protein overexpressed in various cancers including urothelial carcinoma The mechanism of action involves binding to Nectin-4 leading to the disruption of signaling pathways essential for tumor growth and survival Its in vitro activity is characterized within the nanomolar to low micromolar range effectively inhibiting tumor cell proliferation This antibody is widely used in cell models and animal studies to explore its therapeutic potential and efficacy It also plays a significant role in drug screening processes to evaluate novel cancer treatments Experimental concentrations typically depend on the specific research design enabling flexibility in adapting to different experimental requirements
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